Your tips Do a city bus tour (we did the blue bus). You get an overview of SF and see places to go back and take time there later. Do a bay cruise (about 1 hour), you'll get some great photos of the bridge ,Alcatraz and the cityscape. Views over SF from top of Coit Tower. Have clam chowder in sourdough. Have Irish coffee at the buena vista. Beware of dodgey parts of the Tenderloin and SOMA. Go and see Beach Blanket Babylon. Relax and enjoy where you are !
For me San Francisco has a great vibe. It has all the good and bad stuff that you find in any major western city,but it also has something more. It seems to have a soul.(I should have been a 70s hippie !). Unlike most American cities, SF is a very walkable place. A car here is unnecessary and could be a burden. The bus and subway are cheap and can get you to most parts of the city easily. I also found taxis reasonably priced. Hotels are generally expensive, but there are bargains to be had if you shop around. There's a huge range of eating opportunities too.